ABSTRACT
In the past, panretinal photocoagulation (PRP) and vitrectomy (PPV) were the main treatments for proliferative diabetic retinopathy (PDR). In recent years, anti-vascular endothelial growth factor (VEGF) drugs have been used more and more widely in PDR due to their advantages in rapidly subtracting new blood vessels, reducing leakage, and promoting the absorption of blood. The combination of anti-VEGF drugs and PRP in the treatment of PDR, especially high-risk PDR, can increase the rate of neovascularization and prevent some patients with mild to moderate vitreous hemorrhage from PPV. The application of anti-VEGF drugs during the perioperative period of PPV can also reduce bleeding during the operation, shorten the operation time, and reduce surgical complications. Although clinical studies have confirmed that anti-VEGF drugs can be used as an alternative treatment for PRP, most patients require multiple and long-term treatments, which increase the psychological and economic burden of patients. It is expected that the cost of anti-VEGF drugs and the development of long-acting dosage forms can be reduced and bring better efficacy and benefits to PDR patients in the future.
ABSTRACT
Objective To explore the experiences of prostatic hyperplasia patients with dysuria. The thesis is designed to meet the demand of different individuals and to provide basis for reasonable and effective intervention measures. Methods Semi-structure interview is carried out on 16 patients. Data was analyzed by Colaizzi's seven steps of analysis methods. Results The prostatic hyperplasia patients with dysuria experiences were classified into three aspects. The first one was mental experience: the patients used to be healthy and unaware of his illness at first. Later the patients were very painful and lack of correct guidance. The result can lead to incontinence in life and poor quality of sleeping. The second one was psychological experience: the patients have low emotional control ability, which leads to depression and fear-related complications. The patients expect professional guidance and help;therefore, they need to establish a positive attitude towards life. The last one was medical experience:the process of treatment is long and painful, which needs a long period of waiting. Conclusion Patients suffering from dysuria with prostatic hyperplasia experience inconvenience in life. The nurses can help patients to build upon a certain confidence of life by understanding their physical and mental experience and promote physical and mental rehabilitation of patients.
ABSTRACT
Objective To explore the experiences of prostatic hyperplasia patients with dysuria. The thesis is designed to meet the demand of different individuals and to provide basis for reasonable and effective intervention measures. Methods Semi-structure interview is carried out on 16 patients. Data was analyzed by Colaizzi's seven steps of analysis methods. Results The prostatic hyperplasia patients with dysuria experiences were classified into three aspects. The first one was mental experience: the patients used to be healthy and unaware of his illness at first. Later the patients were very painful and lack of correct guidance. The result can lead to incontinence in life and poor quality of sleeping. The second one was psychological experience: the patients have low emotional control ability, which leads to depression and fear-related complications. The patients expect professional guidance and help;therefore, they need to establish a positive attitude towards life. The last one was medical experience:the process of treatment is long and painful, which needs a long period of waiting. Conclusion Patients suffering from dysuria with prostatic hyperplasia experience inconvenience in life. The nurses can help patients to build upon a certain confidence of life by understanding their physical and mental experience and promote physical and mental rehabilitation of patients.
ABSTRACT
BACKGROUND:Based on the blood and urine biochemical changes in different intensities and types of exercise, this research describes the impact of exercise on bone metabolism. Meantime, these biochemical indexes also show a method of marking physiological differences of certain individuals, and also reflect the impact of exercise on bone. These can be regarded as a monitoring index of bone growth and metabolism. OBJECTIVE:To study exercise effect from the biochemical indicators in bone metebolism, and make a further discussion about its influence on bone formation and bone resorption. METHODS:Databases of CNKI and PubMed were retrieved by computer with key words of “exercise; bone metabolism; biochemical indicators” in Chinese and English, respectively, by screening titles and abstracts to search papers related to exercise effects on the blood and urine biochemical indicators. Totaly 236 papers were initialy found, and only 38 papers were included in result analysis. RESULTS AND CONCLUSION: Low-intensity exercise shows less effect on the bone, but excessive exercise is harmful to the bone that can cause stress fractures. What’s worse, it causes a lack of female hormone and reduce bone mass. Exercise can alter the blood and urine biochemical indicators in aspects of types of exercise and intensities. Only the exercise at appropriate intensity makes positive effects on bone formation and resorption, and assists bone mineral density and bone biomechanical indicators to develop exercise prescription and arrange rehabilitation exercises. MechanismS of bone turnover need further discussion at the celular level.